(1S) -1-Phenyl-1,2,3,4-tetrahydroisoquinoline CAS 118864-75-8

Khoom Piav Qhia:

Khoom Lub Npe: (1S) -1-Phenyl-1,2,3,4-tetrahydroisoquinoline CAS TSIS TAU: 118864-75-8

Lub ntsiab lus:

(1S) -1-Phenyl-1,2,3,4-tetrahydro-isopquinoline;

Solifenacin Muaj feem cuam tshuam 11;

Solifenacin Succinate interMediate F;

Tshuaj& Lub Cev Muaj Zog:

Tsos: Dawb dawb

Kev Ntsuas: ≥99.00%

Ceev: 1.065

Kub Point: 338 ℃

Melting Point: 80-82 ℃

Flash Point: 167 ℃

Refractive Index: 1.589

Vapor Siab: 9.87E-05mmHg ntawm 25 ℃

Cov Ntaub Ntawv Kev Nyab Xeeb:

HS Code: 2942000000

(S) -1-phenyl-1,2,3, 4-tetrahydroisoquinoline tuaj yeem siv los npaj sofinacin. Solifenacin succinate, CAS No. 242478-38-2, lub npe tshuaj 1-azabicyclic [2.2.2] octan-8-yl-(1S) -1-phenyl-3, 4-dihydro-1H-isoquinoline-2-formate succinate , Nws yog xaiv muscarinic M3 receptor antagonist tsim los ntawm Nyij Pooj' lub tuam txhab Astellas. Nws tau muag thawj zaug hauv Netherlands, Lub Tebchaws Yelemees, Tebchaws Askiv thiab Denmark xyoo 2004 thiab hauv Suav Tebchaws xyoo 2009. Txog tam sim no, nws tau muag hauv ntau dua 50 lub tebchaws thiab cheeb tsam thoob ntiaj teb, thiab tau dhau los ua cov tshuaj tseem ceeb rau kev kho mob ntawm kev zais zis ntau dhau (OAB) hauv Tebchaws Europe, Tebchaws Asmeskas thiab Nyij Pooj. Pom zoo los ntawm ntau tus tub ceev xwm thiab cov lus qhia. Nws qhov kev npaj yog raws li hauv qab no: (S) -1-phenyl-3, 4-dihydro-1H-isoquinoline-2-formyl chloride (II) tau los ntawm kev sib xyaw ntawm (S) -1-phenyl-1,2,3, 4-tetrahydroisoquinoline (I) nrog triphosgene nyob rau hauv qhov xwm txheej ntawm cov organic hauv paus (tsis muaj zog hauv paus). Compound II tau rhaub ncaj qha nyob rau hauv catalysis ntawm cov organic hauv paus los ntawm ib-lauj kaub txoj kev tsis muaj kev sib cais. Solinacine succinate (IV) tau npaj los ntawm kev sib xyaw ua ke nrog (R) -3 -quinine cycloalcohol kom tau solinacine (III).

Yog tias koj txaus siab rau peb cov khoom lossis muaj lus nug, thov koj xav tiv tauj peb!

Cov khoom lag luam nyob rau hauv patent tau muab rau R& D lub hom phiaj nkaus xwb. Txawm li cas los xij, lub luag haujlwm zaum kawg tshwj xeeb tshaj yog nrog tus neeg yuav khoom.

Cim npe nrov: (1s) -1-phenyl-1,2,3,4-tetrahydroisoquinoline cas 118864-75-8, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, yuav, hauv Tshuag

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